School has been a bit tough this week, getting some of my midterm grades back from last week, which were disappointing. I also dropped my statistics course as I already had a statistics credit, so hopefully I can use my time wisely to catch up with my other courses and train more. I really have nothing against the course, but I'm pretty sure I did pretty terribly that week on all my midterms. The irony is that I dropped Statistics because I was afraid it would skew my average negatively. I actually don't mind Statistics at all. It helps me understand research papers better, and probabilities are cool too, but I don't think we would be cover it in that class. I went and returned my textbook as well. As I'm now missing a bit of KIN credit, I will be taking a course on coaching in the summer to finish my degree.
In Muscle Physiology (UBC KIN 462), we are starting a new unit on training adaptations. We are highlighting the two extremes, which would be Resistance Training and Aerobic Endurance. I suppose there are parts of both in badminton, but I'm definitely more interested in resistance training. I don't think I've ran more than 20 minutes straight in a very long time, and I don't see why I need to as well. For a Kinesiology course, I find it gets a little too detailed, going into biochemistry and molecular biology. I know it's a Physiology course, but it feels so in depth at times that it's like a Faculty of Science - Physiology course. For example, for hypertrophy (increase in muscle cell size as an effect of resistance training), is a calcium independent pathway due to IGF-1 release, which works through 2 different pathways: 1) The PI3K - Akt pathway [via A) PI3K-Akt-mTOR, B) PI3K-Akt-GSK3B, C) PI3K-Akt-FOXO-MuRF1/MAFbx] and 2) Ras-Raf-MEK-ERK pathway. So you can see that you probably just skimmed through all those letters and acronyms and continued reading here. I don't blame you, but to me, this feels like memory work in a way. It doesn't look too much better on a diagram, but this is what I'm struggling with now I guess. If I didn't take biochemistry, I don't know how I would approach this course. For example, PI3K, is phophatidylinositol 3-kinase, which makes no sense to most people (even in my class). From my biochem class, we actually had to draw the structure of it, so at least I can give a good guess. I'm not going to look it up, but if I had to really guess what it was, it's probably an enzyme that adds a phosphate and is some kind of cell membrane receptor. The structure of phosphatidylinositol is actually kind of close to trigylcerides or triacyglycerols, or... fat! Too many triacylglycerols contribute to that much dreaded body fat that people are constantly trying to lose (albeit a bit too quickly at one, I might say). Regardless, glycerol is a sugar backbone which carries 3 chains of fatty acids, unsaturated or saturated. So, if I remember correctly, phosphatidylinositol has a glycerol back bone, 2 fatty acids, and the 3rd one consists of a phosphate and an inositol, which is kind of like a 6 ringed sugar with a bunch of alcohol groups with some that can be phosphorylated (add phosphate). The term 'kinase' refers to an enzyme that adds a phosphate group to something. ANYWAY... perhaps this level of understanding isn't needed, but it bothers me to just memorize PI3K. Another example, which I haven't researched on is GSK3B. It's not GlaxoSmithKline, and the B stands for Beta. So, is there an... Alpha? Why is it 3? Perhaps I'm going to far...
|KIN 462 Notes (Source: Me)|
So in my actual Biochemistry class (UBC BIOC 302), we are doing Nucleic Acids now. We did Fats and Proteins for the first midterm, which didn't go so well, so at least it's more of a new start I guess. If I could take a couple sentences to vent about the midterm, it's not that I don't know my stuff. I studied hard for the exam, even with jetlag and all, but I don't know if it wasn't enough, or if all their questions are like 2 scales above the question you typically see. It's like training for a high school or varsity level tournament, and you play against an International level player. Sure, you know the basic concepts, but apply it in THIS situation! Perhaps I need to dig deeper with my studying and know a little more than I'm expected, but I wouldn't know which direction to take. Anyway, that was like a small paragraph, so some cool things we covered were purine and pyramidine synthesis. What are those? Well, what are nucleic acids? They are structures made with a base, a sugar, and a phosphate backbone and it's the structure of your DNA! So, we definitely need the stuff. As you may or may not know, DNA makes RNA, which makes Protein, so it's quite useful stuff. Something which may be more interesting is that the breakdown of the bases (purines) leads to uric acid and elevated levels of uric acid in the blood can lead to gout! Basically, uric acid crystals form in the extremities and cause the surrounding area to be inflamed. So, a treatment that they use in medicine is a chemical called allopurinol which is supposed to be very similar in structure to hypoxanthine, a structure leading to the formation of uric acid. Allopurinol works to compete with hypoxanthine and ends up inhibiting the enzyme xanthine oxidase, which leads to uric acid. By inhibiting the enzyme, less uric acid is made. See, now THAT is cool. Allopurinol is also a treatment for Lesch-Nyhan Syndrome (Juvenile gout) in which there is an HGPRT deficiency due to a genetic condition. And lastly, as a disclaimer, this is biochemistry and NOT medical advice... anywhere on my blog.
Neuroanatomy (UBC KIN 473) was straight forward this week, but that's because we are doing a midterm next Tuesday. I'm not quite ready yet, but I hope to be ready by the end of this weekend (even with a loss of an hour from Daylight Savings "Spring Forward"), and review on Monday. We did a lot more stuff on motor pathways and upper/lower motor neuron lesions in the first midterm, so this time we will be covering more on the ascending sensory pathways and other structures, like the Basal Ganglia. We also covered Parkinson's Disease (PD) for the majority of the previous class which was pretty cool, as we saw a lot of videos on symptoms, treatments, and the Hoehn and Yahr scale which is used to assess the severity of PD symptoms. So, the 4 hallmark symptoms of PD are bradykinesia (slow & small movements), resting tremor (involuntary shaking at rest), rigidity (stiffness caused by increase in muscle tone), and postural instability. Treatment is usually done by trying to replace dopamine levels, as PD is caused by a degeneration of dopaminergic neurons in the Substantia Nigra, a region in the mid-brain. Unfortunately, the brain has this thing called the blood-brain barrier which is very selective on what can go through, so a precursor to dopamine, L-DOPA, is taken instead. L-DOPA looks a lot like the amino acid Tyrosine, which is a non-essential amino acid in the body, only if you are supplementing with Phenylalanine, which would be an essential one. And for those with a genetic defect in converting phenylalanine to tyrosine, you would get someone with Phenylketonuria (PKU). Pretty cool how things tie together, but to finish off with the PD, treatments are very dosage sensitive and there are on-off swings, where 'off' gives severe PD symptoms, and 'on with dyskinesia' leads to some weird abnormal movements. By far the coolest thing I saw about PD, is that a lot of people suffer from 'freezing', where they cannot start a movement. But if there is some type of visual cue, such as a line on the floor to step over, they can actual step over it with their gait looking a lot like normal! See the video:
I've been doing a lot more footwork for my badminton training, hoping to do at least 15-20 mins before every practice. It seems to be helping tremendously in my movement and I've tried a slight adaptation from what I have observed in the movements of some higher level players. In conjunction with a concept I learned in my Neuromuscular Integration class last year, I'm hoping to develop a more explosive, yet stable footwork base for my badminton. It's not anything new, but I hope to make it look and be as effective as some of the Asian players who move in a similar fashion. The connection with my sport science class is that fact that in gait (walking), the point of greatest instability is not when one foot is in mid-air. It is right when the foot comes down and both feet are in contact with the ground in that instant. I think the reason why is because both feet are on the floor at the same time, there is no saving mechanism because the feet are in an unmovable position until the weight transfer is complete. Given that concept, I am trying not to have both feet on the ground at the same time and instead, slow down the speed of my final steps to the center and use it to push off to the next shot instead. A good example of this is watching Alex Pang in the 2013 Canadian Nationals.
Got the new Yonex Arc Saber 11! I strung it up and it's quite similar to the Arc Saber 10 when I hit overhead shots, but it feels a bit light when I do my pushes and drives. It's not as good as the Arc 10 for me so far, but I need to do a bit more testing. I've played with it twice, with the second time being much better than the first try. Maybe I'll finalize the review next week, after I try it again on Sunday! Overall, it's a pretty good racquet, but I'm not used to the lightness of the head (compared with the 10). Kind of reminds me a bit of the Arc Saber Z-Slash, but not as much of a difference. I definitely like the look of the racquet though :)
|Yonex Arc Saber 11 (Source: Me)|
The 2013 All England Super Series Premier is this week. Some people asked me why I didn't go, but it's because I had exams the previous week (hence, I missed Germany as well). I saw that Michelle Li had a really good run at Eriko Hirose (JPN) so it's nice to see that she's getting closer and closer to challenging the top players! In other tournament news, I will be attending the 2013 Peru International in April, and the next one after that will likely be the 2013 Sudirman Cup! I think this would actually be my first Sudirman Cup, so that will be really cool, as a figure of speech, because Malaysia is going to be very hot! I like Malaysia, but I end up getting sick there... oh well, I'll be more careful this time. The selection criteria has been posted on Badminton Canada so expect the majority of the teams that performed well at the 2013 Canadian Nationals to be there.
At UBC Bookstore, they had a 'Student Appreciation Day' and offered some good discounts on a lot of their merchandise, including clothing, stationary, and general books (non-course related). I stumbled upon Ben Goldacre's 'Bad Science'. He's a UK physician turned epidemiologist and has a column in The Guardian newspaper that tries to debunk bad science. Here's what it's about, as I haven't read the whole book yet:
"We are obsessed with our health. And yet — from the media's "world-expert microbiologist" with a mail-order Ph.D. in his garden shed laboratory, and via multiple health scares and miracle cures — we are constantly bombarded with inaccurate, contradictory, and sometimes even misleading information. Until now. Ben Goldacre masterfully dismantles the questionable science behind some of the great drug trials, court cases, and missed opportunities of our time, but he also goes further: out of the bullshit, he shows us the fascinating story of how we know what we know, and gives us the tools to uncover bad science for ourselves." - from Amazon.ca
It seems like a good read, as it's quite entertaining. I'm hoping to get a copy of "Bad Pharma" when it comes out, which is about the problems of publication bias and more. If you aren't sure about the book, please check out Ben Goldacre on TED. He has two different talks and they are both pretty interesting and he is a pretty good speaker.
Well, for some, the sciences aren't quite as interesting, and it was a pleasant surprise when my girlfriend, Carmen, bought me the second Cyanide and Happiness book! Although terribly crude (to most people), I find it ironic that I am quoting the rapper Eminem, when he said in his song, "Say What You Say",
"I joke when I say I'm the best, in the booth, / But a lot of truth is said in jest"
As he is also terribly crude to some as well, these comics are not for everyone. I will attach a comic which is generally tolerable to most, but they can get quite obscene (you have been warned!). However, if that's what you are looking for, you hit the jackpot for some good laughs ;)
|(Source: interestbuzz.com / Explosm.net)|
McDonald's has coupons! I know, I'm an athlete and I shouldn't be endorsing McDonalds, but I really wonder how bad it could be? When you go eat at McDonalds, you go once in a while (i.e. once a week) and you just have a typical meal, which will cost maybe 1000 calories for a Big Mac meal for $5.50 or so, depending on where you live. Isn't it worse to go to a Cactus Club or a T.G.I.Fridays and have a meal there? Aren't the calories much more in excess of that one McDonald's meal? Would you be having drinks too? So I find it hard to fault McDonald's all the time, I mean they make efforts to follow trends. They got rid of that 'pink slime', they tried to stop using 'trans-fats', and they have excellent coffee! And since it's Roll Up The Rim to Win at Tim Horton's this month, it's interesting to see where people go. As far as I'm concerned, McDonald's has a 100% chance of winning a free coffee if you buy 6 :P And if McDonald's ever wants to sponsor an athlete, I will gladly wear the Golden Arches on my shirt hahaha. Here's an interesting discussion on the '12 Year Old Hamburger' myth. Yeah, I said myth. Click here for the article!
So... I think I'll leave it with that. Interesting enough? See you next week!